diff --git a/extensions/ql-vscode/src/codeql-cli/cli.ts b/extensions/ql-vscode/src/codeql-cli/cli.ts
index c055b4b2b..fe9e02115 100644
--- a/extensions/ql-vscode/src/codeql-cli/cli.ts
+++ b/extensions/ql-vscode/src/codeql-cli/cli.ts
@@ -1818,6 +1818,8 @@ export class CliVersionConstraint {
     "2.12.4",
   );
 
+  public static CLI_VERSION_GLOBAL_CACHE = new SemVer("2.12.4");
+
   constructor(private readonly cli: CodeQLCliServer) {
     /**/
   }
@@ -1887,4 +1889,8 @@ export class CliVersionConstraint {
       CliVersionConstraint.CLI_VERSION_WITH_ADDITIONAL_PACKS_INSTALL,
     );
   }
+
+  async usesGlobalCompilationCache() {
+    return this.isVersionAtLeast(CliVersionConstraint.CLI_VERSION_GLOBAL_CACHE);
+  }
 }
diff --git a/extensions/ql-vscode/src/variant-analysis/run-remote-query.ts b/extensions/ql-vscode/src/variant-analysis/run-remote-query.ts
index 1ccf46042..a45418e3b 100644
--- a/extensions/ql-vscode/src/variant-analysis/run-remote-query.ts
+++ b/extensions/ql-vscode/src/variant-analysis/run-remote-query.ts
@@ -116,12 +116,16 @@ async function generateQueryPack(
 
   let precompilationOpts: string[] = [];
   if (await cliServer.cliConstraints.supportsQlxRemote()) {
-    const ccache = join(originalPackRoot, ".cache");
-    precompilationOpts = [
-      "--qlx",
-      "--no-default-compilation-cache",
-      `--compilation-cache=${ccache}`,
-    ];
+    if (await cliServer.cliConstraints.usesGlobalCompilationCache()) {
+      precompilationOpts = ["--qlx"];
+    } else {
+      const ccache = join(originalPackRoot, ".cache");
+      precompilationOpts = [
+        "--qlx",
+        "--no-default-compilation-cache",
+        `--compilation-cache=${ccache}`,
+      ];
+    }
   } else {
     precompilationOpts = ["--no-precompile"];
   }