diff --git a/extensions/ql-vscode/src/codeql-cli/cli.ts b/extensions/ql-vscode/src/codeql-cli/cli.ts
index 8ff704a36..0982d659d 100644
--- a/extensions/ql-vscode/src/codeql-cli/cli.ts
+++ b/extensions/ql-vscode/src/codeql-cli/cli.ts
@@ -1737,6 +1737,9 @@ export class CliVersionConstraint {
    */
   public static CLI_VERSION_WITH_TRIM_CACHE = new SemVer("2.15.1");
 
+  public static CLI_VERSION_WITH_EXTENSIBLE_PREDICATE_METADATA_IN_QLX =
+    new SemVer("2.16.1");
+
   constructor(private readonly cli: CodeQLCliServer) {
     /**/
   }
@@ -1779,6 +1782,11 @@ export class CliVersionConstraint {
     );
   }
 
+  async supportsExtensiblePredicateMetadataInQlx() {
+    return this.isVersionAtLeast(
+      CliVersionConstraint.CLI_VERSION_WITH_EXTENSIBLE_PREDICATE_METADATA_IN_QLX,
+    );
+  }
   async supportsMrvaPackCreate(): Promise<boolean> {
     return (await this.cli.getFeatures()).mrvaPackCreate === true;
   }
diff --git a/extensions/ql-vscode/test/vscode-tests/cli-integration/variant-analysis/variant-analysis-manager.test.ts b/extensions/ql-vscode/test/vscode-tests/cli-integration/variant-analysis/variant-analysis-manager.test.ts
index 97fe6065f..7c7c13a97 100644
--- a/extensions/ql-vscode/test/vscode-tests/cli-integration/variant-analysis/variant-analysis-manager.test.ts
+++ b/extensions/ql-vscode/test/vscode-tests/cli-integration/variant-analysis/variant-analysis-manager.test.ts
@@ -275,7 +275,15 @@ describe("Variant Analysis Manager", () => {
 
       const queryToRun =
         "Security/CWE/CWE-020/ExternalAPIsUsedWithUntrustedData.ql";
-      const extraQuery = "Telemetry/ExtractorInformation.ql";
+
+      // We only need to preserve queries with extensible predicates if the CLI doesn't support
+      // storing the necessary metadata in the compiled QLX.
+      const needsExtraQueries =
+        !cli.cliConstraints.supportsExtensiblePredicateMetadataInQlx();
+
+      const extraQueries = needsExtraQueries
+        ? ["Telemetry/ExtractorInformation.ql"]
+        : [];
 
       await doVariantAnalysisTest({
         queryPath: join(
@@ -284,7 +292,7 @@ describe("Variant Analysis Manager", () => {
           queryToRun,
         ),
         expectedPackName: "codeql/java-queries",
-        filesThatExist: [queryToRun, extraQuery],
+        filesThatExist: [queryToRun, ...extraQueries],
         filesThatDoNotExist: [],
         qlxFilesThatExist: [],
         dependenciesToCheck: ["codeql/java-all"],