diff --git a/python/ql/lib/semmle/python/frameworks/Httpx.qll b/python/ql/lib/semmle/python/frameworks/Httpx.qll
index ec6a446db2e..fee9a840a19 100644
--- a/python/ql/lib/semmle/python/frameworks/Httpx.qll
+++ b/python/ql/lib/semmle/python/frameworks/Httpx.qll
@@ -9,15 +9,18 @@
 private import python
 private import semmle.python.Concepts
 private import semmle.python.ApiGraphs
+private import semmle.python.frameworks.data.ModelsAsData
 
 /**
+ * INTERNAL: Do not use.
+ *
  * Provides models for the `httpx` PyPI package.
  *
  * See
  * - https://pypi.org/project/httpx/
  * - https://www.python-httpx.org/
  */
-private module HttpxModel {
+module HttpxModel {
   /**
    * An outgoing HTTP request, from the `httpx` library.
    *
@@ -59,8 +62,10 @@ private module HttpxModel {
    */
   module Client {
     /** Get a reference to the `httpx.Client` or `httpx.AsyncClient` class. */
-    private API::Node classRef() {
+    API::Node classRef() {
       result = API::moduleImport("httpx").getMember(["Client", "AsyncClient"])
+      or
+      result = ModelOutput::getATypeNode("httpx.Client~Subclass").getASubclass*()
     }
 
     /** A method call on a Client that sends off a request */
diff --git a/python/ql/src/meta/ClassHierarchy/Find.ql b/python/ql/src/meta/ClassHierarchy/Find.ql
index 7b09a521ef8..6244cf1db0e 100644
--- a/python/ql/src/meta/ClassHierarchy/Find.ql
+++ b/python/ql/src/meta/ClassHierarchy/Find.ql
@@ -18,6 +18,7 @@ private import semmle.python.frameworks.Starlette
 private import semmle.python.frameworks.ClickhouseDriver
 private import semmle.python.frameworks.Aiohttp
 private import semmle.python.frameworks.Fabric
+private import semmle.python.frameworks.Httpx
 import semmle.python.frameworks.data.internal.ApiGraphModelsExtensions as Extensions
 
 class FlaskViewClasses extends FindSubclassesSpec {
@@ -287,6 +288,12 @@ class FlaskBlueprint extends FindSubclassesSpec {
   override API::Node getAlreadyModeledClass() { result = Flask::Blueprint::classRef() }
 }
 
+class HttpxClient extends FindSubclassesSpec {
+  HttpxClient() { this = "httpx.Client~Subclass" }
+
+  override API::Node getAlreadyModeledClass() { result = HttpxModel::Client::classRef() }
+}
+
 bindingset[fullyQualified]
 predicate fullyQualifiedToYamlFormat(string fullyQualified, string type2, string path) {
   exists(int firstDot | firstDot = fullyQualified.indexOf(".", 0, 0) |